Accepting New Patients

Diana Gilligan, MD/PhD

CURRENT APPOINTMENTS

Associate Professor of 医学

Associate Professor of Biochemistry and Molecular Biology

专业

Internal 医学

血液学

语言

英语

病人类型

成年人

RESEARCH PROGRAMS AND AFFILIATIONS

Biochemistry and Molecular Biology

Biomedical Sciences Program

医学

RESEARCH INTERESTS

My research includes studies of the role of microRNA in development of leukemia.

教育 INTERESTS

Teaching hematology to first and second year medical students.

ASSOCIATIONS / MEMBERSHIPS

American Association for Cancer 研究 (AACR)

American Society of 血液学 (ASH)

教育

奖学金: Duke University Medical Center, 1994, Clinical Fellow, 血液学/Oncology

奖学金: Duke University Medical Center, 1993, Postdoctoral Fellow

奖学金: University of North Carolina Hospitals - Chapel Hill, 1989, Postdoctoral Fellow

住院医师: North Carolina Memorial Hospital, 1989, Internal 医学

MD /博士: Albert Einstein College of 医学, 1985, Anatomy and Structural Biology

BA: Radcliffe College, Harvard University, 1976, Biology

RESEARCH ABSTRACT

My research includes studies of the role of microRNA in the progression of acute myeloid leukemia. We are using Nextgen sequencing to profile microRNA from patients with AML or with myeloproliferative disorders that can progress to AML. We have discovered a group of microRNAs that are increased or decreased in patients with AML compared to normal controls. We are continuing to profile patients after induction chemotherapy to determine if the microRNA profile can predict relapse. We are also studying the effects of changes in microRNA expression on cultured leukemic cell lines. This project will lead to better understanding of the targets of the microRNAs and may lead to development of new therapeutics for AML.